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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582032
(Preparation of (2S,4R)-1-((S)-2-(7-(4-(((E)-4-(6-c...)
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Affinity Data
IC50: <100nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
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UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582035
(Preparation of (2S,4R)-1-((S)-2-(2-(2-(2-(4-(((E)-...)
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Affinity Data
IC50: <100nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582033
(Preparation of (2S,4R)-1-((S)-2-(8-(4-(((E)-4-(6-c...)
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Affinity Data
IC50: <100nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582036
(Preparation of (2S,4R)-1-((S)-2-(tert-butyl)-14-(4...)
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Affinity Data
IC50: <100nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582031
(Preparation of pyrrolidine-2-carboxamide of (2S,4R...)
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Affinity Data
IC50: <100nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582034
(US11518759, Compound 7)
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Affinity Data
IC50: 550nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582030
(Preparation of (2S,4R)-1-((S)-2-(5-(4-(((E)-4-(6-c...)
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Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582029
(Preparation of (2S,4R)-1-((S)-2-(4-(4-(((E)-4-(6-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Replicase polyprotein 1a
(Human SARS coronavirus (SARS-CoV))
Shaanxi Panlong Pharmaceutical
US Patent
Ligand
BDBM582028
(US11518759, Compound 1)
Copy SMILES
Copy InChI
Affinity Data
IC50: 550nM
Assay Description:
The inhibitory activity of the compounds against SARS-CoV-2 3CLpro was determined using fluorescence resonance energy transfer.10 μL of the comp...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI